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KMID : 0371420150880050289
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Annals of Surgical Treatment and Research
2015 Volume.88 No. 5 p.289 ~ p.293
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Giant malignant insulinoma
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Karavias Dimitrios
Habeos Ioannis
Maroulis Ioannis
Kalogeropoulou Christina
Tsamandas Athanasios
Chaveles Ioannis
Karavias Dionissios
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Abstract
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Insulinomas are the most common pancreatic neuroendocrine tumors. Most insulinomas are benign, small, intrapancreatic solid tumors and only large tumors have a tendency for malignancy. Most patients present with symptoms of hypoglycemia that are relieved with the administration of glucose. We herein present the case of a 75-year-old woman who presented with an acute hypoglycemic episode. Subsequent laboratory and radiological studies established the diagnosis of a 17-cm malignant insulinoma, with local invasion to the left kidney, lymph node metastasis, and hepatic metastases. Patient symptoms, diagnostic and imaging work-up and surgical management of both the primary and the metastatic disease are reviewed.
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KEYWORD
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Insulinoma, PNET, Giant tumor
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